Melphalan: What You Need to Know

If you or someone you care about is facing cancer treatment, you might hear about a drug called Melphalan. It’s one of the chemotherapy medicines doctors use to fight certain types of cancer by stopping cancer cells from growing and spreading.

Melphalan is often prescribed for multiple myeloma and ovarian cancer, but also for other types. It works by interfering with the DNA inside cancer cells, which keeps them from multiplying. This can help shrink tumors or slow down their growth.

How Is Melphalan Given?

This drug can come as a pill or be administered through an IV, depending on the type of cancer and treatment plan. The doctor decides the right dose based on your specific situation. It’s important to stick to the schedule because the timing affects how well the treatment works.

Because it targets fast-growing cells, Melphalan can also affect healthy cells, which leads to some side effects. Common ones include nausea, vomiting, low blood counts, and mouth sores. Your medical team will help you manage these and watch for any serious issues.

What Should You Watch For?

Besides the usual side effects, Melphalan can weaken your immune system, making infections more likely. It’s smart to avoid anyone who’s sick and keep good hygiene during treatment. Also, tell your doctor if you experience unusual bleeding, bruising, or persistent fever, as these might signal more serious problems.

Before starting Melphalan, doctors usually run tests to check how well your liver and kidneys work. These organs help clear the drug from your body, so their health impacts how your treatment goes.

It’s normal to have questions and concerns about chemotherapy, but knowing how Melphalan works and what to expect can make the process less intimidating. Trust your healthcare providers and keep communication open—they’re there to support you through every step.